1. 个人简介:
何玉涛,理学博士,副研究员,硕士生导师。2009年毕业于兰州大学,获学士学位,2016年获得兰州大学有机化学专业博士学位。随后,分别在韩国(KAIST)和日本(OIST)从事博士后研究,2020年回国入职永利集团。主要研究方向为活性杂环化合物高效构建,天然产物的结构修饰,有机合成新反应、新方法:包括:可见光催化、自由基化学以及药物化学。曾以项目负责人 PI 身份获得并管理日本科研补助金 (JSPS KAKENHI)。2020年进入永利集团工作,目前为止共发表SCI论文30篇,总引1000余次,其中以第一作者或通讯作者身份发表SCI论文15篇,单篇最高引用132次,申请发明专利2项。
非常欢迎具有科研理想、勤奋努力的同学加入团队,共同奋斗和成长!
2. 研究方向:
(1)活性杂环化合物高效构建,天然产物的结构修饰,药物化学
(2)有机合成新反应、新方法 (可见光催化、自由基化学、过渡金属催化)
3. 代表性论文:
T.-T. Yuan, J. Chen, L. N. Pham, L. V. White, P. Lan, M. L. Coote, M. G. Banwell,* Y.-T. He*. Visible Light-induced Syntheses of Unsymmetrical Methylene-bridged bis-Heterocycles via an Alkoxy Radical Relay Reaction. Org. Chem. Front. 2023, 10, 4649.
Y. Chen,# G.-Y. Zhang,# C. Guo, P. Lan, M. G. Banwell*, Y.-T. He*. Silver-Promoted Radical Ring-Opening/Pyridylation of Cyclobutanols with N-Methoxypyridinium Salts. Chem. Eur. J. 2022, 28, e202104627.
Y.-T. He, L.-X. Li, X. Lin, B.-L. Hou*, C.-C. Li*. Synthesis of Various Bridged Ring Systems via Rhodium-Catalyzed Bridged (3+2) Cycloadditions. Org. Lett. 2022, 24, 186.
Y.-T. He, A. Karimata, O. Gladkovskaya, E. Khaskin, R. R. Fayzullin, A. Sarbajna, and J. R. Khusnutdinova*C–C Bond Elimination from High-Valent Mn Aryl Complexes. Organometallics2021, 40, 2320.
J. Jeon,# Y.-T. He#, S. Shin, S. Hong*. Visible-Light-Induced Remote Pyridyl ortho-Migration for Trifluoromethylative Pyridylation of Unactivated Alkenes. Angew. Chem. Int. Ed. 2020, 59, 281.
A. Sarbajna,#Y.-T. He#, M. H. Dinh, O. Gladkovskaya, S. M. W. Rahaman, A. Karimata, E. Khaskin, S. Lapointe, R. R. Fayzullin, J. R. Khusnutdinova*. Aryl-X Bond-Forming Reductive Elimination from High-Valent Mn-Aryl Complexes. Organometallics2019, 38, 4409.
Y.-T. He, D. Kang, I. Kim, S. Hong*. Metal-Free Photocatalytic Trifluoromethylative Pyridylation of Unactivated Alkenes. Green Chem. 2018, 20, 5209.
Y.-T. He, J. Won, J. Kim, B. Park, T. Kim, M.-H. Baik*, S. Hong*. One-Pot Bifunctionalization of Unactivated Alkenes, P(O)–H Compounds, and N-Heteroarenium Salts for the Construction of β-Pyridyl Alkylphosphonates. Org. Chem. Front. 2018, 5, 2595.
Y.-T. He, L.-H. Li, Q. Wang, W. Wu, Y.-M. Liang* Synthesis of β-Difluoroalkylated Acrylonitriles in the Presence of Copper Powder. Org. Lett. 2016, 18, 5158.
Y.-T. He, Q. Wang, L.-H. Li, X.-Y. Liu, P.-F. Xu, Y.-M. Liang* Palladium-Catalyzed Intermolecular Aryldifluoromethylation of Alkynes. Org. Lett.2015, 17, 5188.
Y.-T. He, Q. Wang, J. Zhao, X.-Z. Wang, Y.-F. Qiu, Y.-C. Yang, J.-Y. Hu, X.-Y. Liu, Y.-M. Liang* Copper-Catalyzed Cascade Cyclization for the Synthesis of Trifluoromethyl-Substituted Spiro-2H-azirines from 1,6-Enynes. Adv. Synth. Catal. 2015, 357, 3069.
Y.-T. He, Q. Wang, J. Zhao, X.-Y. Liu, P.-F. Xu, Y.-M. Liang* The copper-catalyzed synthesis of β-trifluoromethylated acrylonitriles and trifluoromethyl-substituted 2H-azirines. Chem. Commun. 2015, 51, 13209.
Y.-T. He, L.-H. Li, Z.-Z. Zhou, H.-L. Hua, Y.-F. Qiu, X.-Y. Liu, Y.-M. Liang* Copper-Catalyzed Three-Component Cyanotrifluoromethylation/Azidotrifluoromethylation and Carbocyclization of 1,6-Enynes. Org. Lett. 2014, 16, 3896.
Y.-T. He, L-H. Li, Y.-F. Yang, Z.-Z. Zhou, H.-L. Hua, X.-Y. Liu, Y.-M. Liang* Copper-Catalyzed Intermolecular Cyanotrifluoromethylation of Alkenes. Org. Lett.2014, 16, 270.
Y.-T. He, L.-H. Li, Y.-F. Yang, Y.-Q. Wang, J.-Y. Luo, X.-Y. Liu, Y.-M. Liang* Copper-catalyzed synthesis of trifluoromethyl-substituted isoxazolines. Chem. Comm.2013, 49, 5687.
4.联系方式:
Email:heyutao7@jnu.edu.cn
地址:永利集团第二理工楼617